Behavioral neuroscience, 1997-02, Vol.111 (1), p.129-136
1997
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- Autor(en) / Beteiligte
- Titel
- Conditioned Taste Aversions and Drugs of Abuse: A Reinterpretation
- Ist Teil von
- Behavioral neuroscience, 1997-02, Vol.111 (1), p.129-136
- Ort / Verlag
- Washington, DC: American Psychological Association
- Erscheinungsjahr
- 1997
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- A new hypothesis (and supporting data) provides a solution to the 25-year-old paradox whereby positively reinforcing drugs of abuse also support a conditioned taste aversion (CTA). The results show that unlike LiCl-induced CTAs, morphine- and cocaine-induced suppression of conditioned stimulus (CS) intake depends on the rewarding properties of the gustatory CS. This finding argues against the long-standing CTA interpretation in favor of a new reward comparison account. That is, rats decrease intake of a gustatory CS following taste-drug pairings because the value of the CS is outweighed by that of a highly reinforcing psychoactive drug. Suppression of CS intake, then, is a consequence of the well-documented positive reinforcing, rather than the hypothetical aversive, properties of drugs of abuse.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0735-7044eISSN: 1939-0084DOI: 10.1037/0735-7044.111.1.129Titel-ID: cdi_proquest_miscellaneous_78938136
- Format
- –
- Schlagworte
- Animal, Animals, Association Learning - drug effects, Aversion Conditioning, Avoidance Learning - drug effects, Behavioral psychophysiology, Biological and medical sciences, Cocaine, Cocaine - pharmacology, Conditioning, Classical - drug effects, Dose-Response Relationship, Drug, Drinking - drug effects, Drug abuse, family and consumer science, family studies, Female, Fundamental and applied biological sciences. Psychology, human development, human nutrition, Hypotheses, Injections, Intraperitoneal, Injections, Subcutaneous, Lithium, Lithium Chloride - pharmacology, Male, Morphine, Morphine - pharmacology, Motivation, Neurotransmission and behavior, nutrition physiology, Psychology, Psychology. Psychoanalysis. Psychiatry, Psychology. Psychophysiology, Rats, Rats, Sprague-Dawley, Reinforcement, Rewards, Saccharin, Sodium, Street Drugs - pharmacology, Taste, Taste - drug effects, Taste Stimulation