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Laparoscopic surgery is associated with less tumour growth stimulation than conventional surgery: An experimental study
Ist Teil von
British journal of surgery, 1997-03, Vol.84 (3), p.358-361
Ort / Verlag
Bristol: John Wiley & Sons, Ltd
Erscheinungsjahr
1997
Quelle
Wiley Online Library Journals Frontfile Complete
Beschreibungen/Notizen
Background The role of laparoscopic surgery for malignant disease is controversial. To evaluate differences in tumour growth after conventional and laparoscopic surgery, an experimental study was performed in rats.
Methods After intraperitoneal injection of CC‐531 colonic cancer cells or subcapsular renal implantation of CC‐531 cancer cells, rats underwent either laparoscopically assisted small bowel resection, open small bowel resection or anaesthesia only. Peritoneal tumour growth and subcapsular renal tumour growth were assessed after operation.
Results Peritoneal tumour growth was the least after anaesthesia only (P<0.05) and less after laparoscopic than open resection (P<0·05). Subcapsular renal tumour growth after either laparoscopic resection or anaesthesia only was less than after open resection (P<0·01).
Conclusion Laparoscopic surgery was associated with less tumour growth than conventional surgery in this experimental study.