Details

Autor(en) / Beteiligte

• Gealow, Kendra
• Solien, Eric
• Bianco, Richard
• Grandjean, Pierre

Titel

Effect of Adaptive Pulse Train Duration on Latissimus Dorsi Blood Flow

Ist Teil von

• Artificial organs, 1997-03, Vol.21 (3), p.243-246

Ort / Verlag

Boston, USA: Blackwell Science, Inc

Erscheinungsjahr

1997

Quelle

MEDLINE

Beschreibungen/Notizen

• Blood flow, intramuscular pressure, and stroke work of the trainedlatissimus dorsi muscle (LD) were measured during electrical stimulation atcontraction ratesbetween 20 and 160/min using pulse trains of 2 to 6 pulses in length. Epimysialelectrodes and intramuscular pressure sensors were implanted in the LD of 5dogs. The muscleremained in situ. After 12 weeks of a progressive training protocol, LD bloodflow (BF) was measured using an ultrasonic flow probe and work (SW) wasdetermined from the measuredforce and shortening. For pulse trains of 2 or 3 pulses, BF increased with rate,and SW was maintained at all rates. For 4 pulses, BF and SW decreased when thecontraction rateexceeded 120/min. SW decreased above 100/min and 80/min for 5 and 6 pulses,respectively. An upper rate limit dependent upon the pulse train durationexists above which BF and SWdecline. Exceeding these upper rate limits should be avoided incardiomyoplasty. Excessive stimulation rates could be detrimental to the muscleby creating a metabolicinsufficiency or ischemia. The cardiac assistance benefit is compromised as SWdeclines during high contraction rates of long pulse train duration.