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Carotenoids and the Immune Response
The Journal of nutrition, 1989-01, Vol.119 (1), p.112-115
1989

Details

Autor(en) / Beteiligte
Titel
Carotenoids and the Immune Response
Ist Teil von
  • The Journal of nutrition, 1989-01, Vol.119 (1), p.112-115
Ort / Verlag
United States: Elsevier Inc
Erscheinungsjahr
1989
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
  • There is growing evidence from in vitro and in vivo laboratory animal studies that β-carotene can protect phagocytic cells from autooxidative damage, enhance T and B lymphocyte proliferative responses, stimulate effector T cell functions, and enhance macrophage, cytotoxic T cell and natural killer cell tumoricidal capacities, as well as increase the production of certain interleukins. Many of these effects have also been seen with carotenoids lacking provitamin A activity but having the antioxidant and singlet oxygen quenching capacities of β-carotene. The association of immunoenhancement with decreased tumor burden in animals given carotenoids suggests a potential explanation for the epidemiological data linking lower carotenoid status with higher incidences of certain cancers. Since vitamin A is a relatively poor antioxidant and cannot quench singlet oxygen, β-carotene may have more importance as a nutrient than simply serving as a precursor of vitamin A.

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