Annual review of neuroscience, 1997-01, Vol.20 (1), p.483-532
1997
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- Autor(en) / Beteiligte
- Titel
- Pax-6 in development and evolution
- Ist Teil von
- Annual review of neuroscience, 1997-01, Vol.20 (1), p.483-532
- Ort / Verlag
- Palo Alto, CA: Annual Reviews
- Erscheinungsjahr
- 1997
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Pax-6 is a member of the Pax gene class and encodes a protein containing a paired domain and a homeodomain. The molecular characterization of Pax-6 genes from species of different animal phyla and the analysis of Pax-6 function in the developing eyes and central nervous system of vertebrates, Drosophila melanogaster, and Caenorhabditis elegans suggest that Pax-6 homologues share conserved functions. In this review, we present recent data on the structural and functional characterization of Pax-6 homologues from species of different animal phyla. We discuss the implications of these findings for our understanding of the development and evolution of eyes and nervous systems.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0147-006XeISSN: 1545-4126DOI: 10.1146/annurev.neuro.20.1.483Titel-ID: cdi_proquest_miscellaneous_78844714
- Format
- –
- Schlagworte
- Animals, Biological and medical sciences, Biological Evolution, Development. Senescence. Regeneration. Transplantation, DNA-Binding Proteins - metabolism, DNA-Binding Proteins - physiology, Eye Proteins, Fundamental and applied biological sciences. Psychology, Homeodomain Proteins, Paired Box Transcription Factors, PAX6 Transcription Factor, Repressor Proteins, Transcription Factors - metabolism, Transcription Factors - physiology, Vertebrates: nervous system and sense organs