Biomedicine & pharmacotherapy, 1996, Vol.50 (10), p.480-487
1996
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Details
- Autor(en) / Beteiligte
- Titel
- Contribution of cohort studies in understanding HIV pathogenesis: introduction of the GRIV cohort and preliminary results
- Ist Teil von
- Biomedicine & pharmacotherapy, 1996, Vol.50 (10), p.480-487
- Ort / Verlag
- France: Elsevier SAS
- Erscheinungsjahr
- 1996
- Quelle
- Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
- Beschreibungen/Notizen
- In the present paper we review studies performed on HIV-infected patients cohorts in order to understand AIDS disease development. The interplay between diverse factors such as the HIV envelope proteins, cellular co-receptors, the immune response with chemokines and cytokines production define the viral tropisrn, cytopathicity and progression of HIV disease. We present the trends of the research particularly in the domain concerning host genetics. In this context, we describe the GRIV cohort of fast and slow/non-progressors, and its use for understanding basic features of the yet unknown HIV pathogenesis mechanisms.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0753-3322eISSN: 1950-6007DOI: 10.1016/S0753-3322(97)89278-5Titel-ID: cdi_proquest_miscellaneous_78704203
- Format
- –
- Schlagworte
- Acquired Immunodeficiency Syndrome - genetics, Acquired Immunodeficiency Syndrome - immunology, Acquired Immunodeficiency Syndrome - virology, Adult, AIDS/HIV, Chemokines - genetics, Cohort Studies, Female, HIV - pathogenicity, HIV Infections - genetics, HIV Infections - immunology, HIV Infections - virology, Humans, Major Histocompatibility Complex, Male, Receptors, CCR4, Receptors, Chemokine, Receptors, Cytokine - genetics