Cancer letters, 1996-11, Vol.108 (2), p.157-162
1996
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Breast cancer prognostic significance of some modified urinary nucleosides
- Ist Teil von
- Cancer letters, 1996-11, Vol.108 (2), p.157-162
- Ort / Verlag
- Shannon: Elsevier Ireland Ltd
- Erscheinungsjahr
- 1996
- Quelle
- Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
- Beschreibungen/Notizen
- The prognostic significance of six urinary modified nucleosides, 5-methylcytidine (5-MeCyd), 4-acetylcytidine (4-AcCyd), 1-methylinosine (1-MeIno), 1-methyladenosine (1-MeAdo), 7-methylguanosine (7-MeGua) and pseudouridine (Ψ-Urd) was evaluated in 68 breast cancer patients of the specialized cancer hospital of Lyon (France). Excretions of 1-MeIno and 1-MeAdo were significantly higher in patients hospitalized in the medical rather than surgical ward, reflecting more advanced disease, and also among patients who died within 5 years of follow-up as compared to those still alive. These results suggest an unfavourable prognostic significance of high urinary excretion of 1-MeIno and 1-MeAdo in breast cancer patients.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0304-3835eISSN: 1872-7980DOI: 10.1016/S0304-3835(96)04393-5Titel-ID: cdi_proquest_miscellaneous_78636584
- Format
- –
- Schlagworte
- Biological and medical sciences, Biomarkers, Tumor - urine, Breast cancer, Breast Neoplasms - pathology, Breast Neoplasms - urine, Female, Gynecology. Andrology. Obstetrics, Humans, Male, Mammary gland diseases, Medical sciences, Middle Aged, Modified nucleosides, Nucleosides - urine, Prognosis, Tumors, Urinary excretion