Physiology & behavior, 1996-11, Vol.60 (5), p.1307-1310
1996
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Peripheral β-Adrenoreceptors and Stress-Induced Hypercholesterolemia in Rats
- Ist Teil von
- Physiology & behavior, 1996-11, Vol.60 (5), p.1307-1310
- Ort / Verlag
- Cambridge: Elsevier Inc
- Erscheinungsjahr
- 1996
- Quelle
- Access via ScienceDirect (Elsevier)
- Beschreibungen/Notizen
- Three experiments were conducted examining the contribution of β-adrenergic receptors to stress-induced cholesterol increases. Rats were exposed to 3 90-min sessions of inescapable tailshock, or left undisturbed in their home cage. Propranolol, a nonselective β-blocker, attenuated the stress-induced cholesterol increase when administered prior to the daily shock session. Atenolol, a β-1 specific antagonist, also attenuated the stress-induced cholesterol increase. Butoxamine, a β-2 specific antagonist, had no effect on the stress-induced cholesterol increases. Results are discussed in terms of catecholamine-stimulated free fatty acid (FFA) release as a potential mechanism for producing stress-induced hypercholesterolemia.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0031-9384eISSN: 1873-507XDOI: 10.1016/S0031-9384(96)00255-7Titel-ID: cdi_proquest_miscellaneous_78533477
- Format
- –
- Schlagworte
- Adrenergic beta-Antagonists - pharmacology, Animals, Atenolol, Atenolol - pharmacology, Behavioral psychophysiology, Biological and medical sciences, Butoxamine, Butoxamine - pharmacology, Cholesterol, Electroshock, Fatty Acids, Nonesterified - blood, Free fatty acids, Fundamental and applied biological sciences. Psychology, Hypercholesterolemia - blood, Hypercholesterolemia - etiology, Hypercholesterolemia - physiopathology, Male, Neurotransmission and behavior, Propranolol, Propranolol - pharmacology, Psychology. Psychoanalysis. Psychiatry, Psychology. Psychophysiology, Rats, Receptors, Adrenergic, beta - physiology, Receptors, Adrenergic, beta-1 - drug effects, Receptors, Adrenergic, beta-1 - physiology, Receptors, Adrenergic, beta-2 - drug effects, Receptors, Adrenergic, beta-2 - physiology, Stress, Stress, Psychological - complications, Stress, Psychological - physiopathology, β-Adrenergic receptors