Thrombosis research, 1996-03, Vol.81 (5), p.577-581
1996
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Details
- Autor(en) / Beteiligte
- Titel
- A racial difference in the prevalence of the Arg506->Gln mutation
- Ist Teil von
- Thrombosis research, 1996-03, Vol.81 (5), p.577-581
- Ort / Verlag
- New York, NY: Elsevier Ltd
- Erscheinungsjahr
- 1996
- Quelle
- Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
- Beschreibungen/Notizen
- Several recent studies have reported that the factor V Arg506→Gln mutation is present in 3–10% of adults of European descent. To determine if the prevalence is comparable among Blacks, we have initiated a casecontrol study in a large urban hospital in Atlanta which serves a substantial black population. We have evaluated 131 black subjects with confirmed venous or arterial thrombosis and 61 black subjects without a history of thrombosis. Only one case and one control were positive for the Arg506→Gln mutation. We conclude that the mutation is more common among Whites than Blacks.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0049-3848eISSN: 1879-2472DOI: 10.1016/0049-3848(96)00032-1Titel-ID: cdi_proquest_miscellaneous_78520889
- Format
- –
- Schlagworte
- African Continental Ancestry Group, APC-R, Arginine - genetics, Base Sequence, Biological and medical sciences, Blood and lymphatic vessels, Cardiology. Vascular system, Case-Control Studies, Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous, European Continental Ancestry Group, Factor V - genetics, Glycine - genetics, Humans, Medical sciences, Molecular Sequence Data, Point Mutation, protein C, race prevalence, thrombosis