Details

Autor(en) / Beteiligte

• OGBOGU, V.C.
• STOREY, D.M.

Titel

In‐vivo encapsulation and killing of Litomosoides carinii in white rats

Ist Teil von

• Parasite immunology, 1988-03, Vol.10 (2), p.219-235

Ort / Verlag

Oxford, UK: Blackwell Publishing Ltd

Erscheinungsjahr

1988

Quelle

MEDLINE

Beschreibungen/Notizen

• Summary Ultrastructural studies revealed that in albino rats Litomosoides carinii was encapsulated and eventually killed in the pleural cavity by adherent host cells. Encapsulation was an organized cellular reaction which sequestered and eventually degraded the parasites. The process evolved in three phases: primary accumulation of host cells, especially eosinophils and macrophages, around the parasites with concentration of eosinophils on the parasite surface; secondary transformation of macrophages into epithclioid cells which replaced eosinophils on the parasite surface; finally, dead parasites became calcified and were gradually degraded within a tough, compacted fibrotic capsule.