Details

Autor(en) / Beteiligte

• Serafini, Paulo
• Stone, Bronte
• Kerin, John
• Batzofin, Joel
• Quinn, Patrick
• Marrs, Richard P.

Titel

Occurrence of a spontaneous luteinizing hormone surge in superovulated cycles—predictive value of serum progesterone

Ist Teil von

• Fertility and sterility, 1988-01, Vol.49 (1), p.86-89

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

1988

Quelle

MEDLINE

Beschreibungen/Notizen

• A preovulatory increase in serum progesterone (P) precedes the occurrence of an endogenous luteinizing hormone (LH) surge in a majority of women. This study evaluates whether a single daily measurement of serum P could reliably identify a spontaneous LH surge in women undergoing controlled ovarian hyperstimulation. Eighty-four infertile women received either clomiphene citrate and human menopausal gonadotropin (hMG), or hMG alone. Serum P levels were increased significantly the morning of the day of an endogenous LH surge (P<0.01). A 2-fold rise in the serum P levels was associated with a predictability of 64.4% of a LH surge; however, a 4-fold increase in serum P could accurately predict a spontaneous endogenous LH discharge in 93.3% (P<0.001) of cases.