Details

Autor(en) / Beteiligte

• Anderson, George M.
• Freedman, Daniel X.
• Cohen, Donald J.
• Volkmar, Fred R.
• Hoder, E. Lawrence
• McPhedran, Peter
• Minderaa, Ruud B.
• Hansen, Carl R.
• Young, J. Gerald

Titel

WHOLE BLOOD SEROTONIN IN AUTISTIC AND NORMAL SUBJECTS

Ist Teil von

• Journal of child psychology and psychiatry, 1987-11, Vol.28 (6), p.885-900

Ort / Verlag

Oxford, UK: Blackwell Publishing Ltd

Erscheinungsjahr

1987

Link zum Volltext

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• Whole blood serotonin and tryptophan were measured in 87 normal subjects and in 40 autistic subjects. Whole blood serotonin concentration (mean ± SE) were significantly higher in drug‐free (N= 21) autistics (205 ± 16 ng/ml) that in normal (136 ± 5.4 ng/ml) The Gaussian distribution of serotonin level of the unmidicated autistic group suggests the elevation was not due to a subgroup of autistic subject Autistics medicated with medicated with anticonvulsants or neuroleptics had significantly lower serortonin levels than did drug‐free autistic subjects Whole blood trytophan levels and platelet counts were similar in the autistic and normal groups. The possible cause of the hyerserotonemia of autism are discussed