Details

Autor(en) / Beteiligte

• Solomon, Scott D.
• Kytömaa, Harri
• Celi, Ann C.
• Maas, Luis C.
• Chou, Lisa
• Hopkins, Julie
• Caguioa, Eduardo
• Lee, Richard T.

Titel

Myocardial Tissue Characterization by Autocorrelation of Two-dimensional Ultrasonic Backscatter

Ist Teil von

• Journal of the American Society of Echocardiography, 1994-11, Vol.7 (6), p.631-640

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

1994

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• To evaluate a novel method for determining the spatial distribution of echocardiographic information based on the two-dimensional. autocorrelation function, echocardiographic images were obtained from specific regions of interest from 10 healthy volunteers, seven patients with genetically defined hypertrophy cardiomyopathy, and nine patients with pressure-overload hypertrophy. The wavelength of distinct peaks from the two-dimensional autocorrelation of the images was compared between groups of patients and demonstrated a significant decrease, in the mean length scale associated with distinct secondary correlation peaks in patients with hypertrophy cardiomyopathy or pressure-overload hypertrophy compared with healthy volunteers (p = 0.0009). With a discriminating wavelength of 3.3 mm, the sensitivity of this technique for detecting abnormal myocardium was 84% with a specificity of 89%. This study suggests that ultrasonic tissue characterization based on the two-dimensional autocorrelation function may have potential for distinguishing normal from abnormal myocardium and provides a rationale for textural approaches to ultrasonic tissue characterization.