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Science (American Association for the Advancement of Science), 1987-07, Vol.237 (4814), p.525-527
Ort / Verlag
Washington, DC: The American Association for the Advancement of Science
Erscheinungsjahr
1987
Quelle
MEDLINE
Beschreibungen/Notizen
A defined medium (H-1) was developed for cultivation of the suckling mouse cataract agent, Spiroplasma mirum, a fastidious member of the class Mollicutes that causes cataracts and chronic brain infection in inoculated neonate mice. The H-1 medium was used to show the importance of sphingomyelin as a growth factor for the culture of the spiroplasma in vitro. The growth of Spiroplasma mirum and the pathology it induces in sphingomyelin-rich tissues in vivo may be related to this dependency.