Details

Autor(en) / Beteiligte

• Messing, Bernard
• Lémann, Marc
• Landais, Paul
• Gouttebel, Marie-Claude
• Gérard-Boncompain, Michèle
• Saudin, Francois
• Vangossum, André
• Beau, Philippe
• Guédon, Claire
• Barnoud, Didier
• Beliah, Martine
• Joyeux, Henri
• Bouletreau, Paul
• Robert, Dominique
• Matuchansky, Claude
• Leverve, Xavier
• Lerebours, Eric
• Carpentier, Yvon
• Rambaud, Jean-Claude

Titel

Prognosis of patients with nonmalignant chronic intestinal failure receiving long-term home parenteral nutrition

Ist Teil von

• Gastroenterology (New York, N.Y. 1943), 1995-04, Vol.108 (4), p.1005-1010

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

1995

Quelle

MEDLINE

Beschreibungen/Notizen

• Background/Aims: Long-term survival of patients with intestinal failure requiring home parenteral nutrition (HPN) has been only partly shown. Therefore, we described the survival of these patients and explored prognosis factors. Methods: Two hundred seventeen noncancer non-acquired immunodeficiency syndrome adult patients presenting with chronic intestinal failure enrolled from January 1980 to December 1989 in approved HPN programs in Belgium and France; prognosis factors of survival were explored using multivariate analysis. Data were updated in March 1991; not one of the patients was lost to follow-up. Results: Seventy-three patients died during the survey, and the mortality rate related to HPN complications accounted for 11% of deaths. Probabilities of survival at 1, 3, and 5 years were 91%, 70%, and 62%, respectively. Three independent variables were associated with a decreased risk of death: age of patients younger than 40 years, start of HPN after 1987, and absence of chronic intestinal obstruction. In patients younger than 60 years of age included after 1983 with a very short bowel, who could represent suitable candidates for small bowel transplantation, the 2-year survival rate was 90%, a prognosis that compared favorably with recent reports of survival after small bowel transplantation. Conclusions: HPN prognosis compares favorably with recent reports of survival after small bowel transplantation.