Archives of virology, 1986-01, Vol.89 (1-4), p.203-212
1986
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Details
- Autor(en) / Beteiligte
- Titel
- Changes in membrane permeability in cells infected by human cytomegalovirus
- Ist Teil von
- Archives of virology, 1986-01, Vol.89 (1-4), p.203-212
- Ort / Verlag
- Wien: Springer
- Erscheinungsjahr
- 1986
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- To analyze whether human cytomegalovirus could induce changes in membrane permeability we studied both Hygromycin B (HyB) inhibition of protein synthesis and glycine and choline uptake during viral replication. A higher sensitivity to HyB was observed both immediately after virus adsorption and in concomitance with the release of viral progeny. HyB sensitivity immediately after virus adsorption was not associated with changes in membrane permeability to glycine and choline while 60 hours p.i. a remarkable increase in choline uptake was detected.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0304-8608eISSN: 1432-8798DOI: 10.1007/BF01309889Titel-ID: cdi_proquest_miscellaneous_76887800
- Format
- –
- Schlagworte
- Biological and medical sciences, Biological Transport - drug effects, Cell Membrane Permeability - drug effects, Cell Transformation, Viral, choline, Choline - metabolism, cytomegalorirus (human), Cytomegalovirus - genetics, DNA Replication - drug effects, Embryo, Mammalian, Female, Fibroblasts - drug effects, Fundamental and applied biological sciences. Psychology, glycine, Glycine - metabolism, Humans, hygromycin B, Hygromycin B - pharmacology, Indicators and Reagents, Kinetics, membrane permeability, Microbiology, Onium Compounds - metabolism, Organophosphorus Compounds - metabolism, Pregnancy, Protein Biosynthesis, protein synthesis, Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains, Virology, Virus Replication - drug effects