The Journal of Antibiotics, 1994/10/25, Vol.47(10), pp.1104-1109
1994
Details
- Autor(en) / Beteiligte
- Titel
- NISAMYCIN, A NEW MANUMYCIN GROUP ANTIBIOTIC FROM Streptomyces sp. K106: I. TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES
- Ist Teil von
- The Journal of Antibiotics, 1994/10/25, Vol.47(10), pp.1104-1109
- Ort / Verlag
- Tokyo: JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
- Erscheinungsjahr
- 1994
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Nisamycin, a new manumycin group antibiotic, was isolated from the culture broth of Streptomyces sp. K106. This strain was designated to genus Streptomyces by the taxonomic features. Nisamycin was purified by ethyl acetate extraction, silica gel column chromatography, preparative silica gel TLC, and Sephadex LH-20 column chromatography as a pale yellow powder. Nisamycin is active against Gram-positive bacteria and fungi, and exhibits a cytotoxic activity.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0021-8820eISSN: 1881-1469DOI: 10.7164/antibiotics.47.1104Titel-ID: cdi_proquest_miscellaneous_76817961
- Format
- –
- Schlagworte
- Animals, Anti-Bacterial Agents - biosynthesis, Anti-Bacterial Agents - chemistry, Anti-Bacterial Agents - pharmacology, Antibacterial agents, Antibiotics. Antiinfectious agents. Antiparasitic agents, Biological and medical sciences, Cell Division - drug effects, Chemical Phenomena, Chemistry, Physical, Fermentation, Fungi - drug effects, Gram-Positive Bacteria - drug effects, Humans, Leukemia P388 - pathology, Medical sciences, Melanoma, Experimental - pathology, Mice, Microscopy, Electron, Scanning, Pharmacology. Drug treatments, Polyenes - chemistry, Polyenes - metabolism, Polyenes - pharmacology, Streptomyces, Streptomyces - classification, Streptomyces - metabolism, Streptomyces - ultrastructure, T-Lymphocytes - cytology, Tumor Cells, Cultured