Details

Autor(en) / Beteiligte

• Pathak, Rameshwar
• Padmanabhan, Vellore T.
• Tortolani, Anthony J.
• Ong, Lawrence Y.
• Hall, Michael H.
• Pizzarello, Roy A.

Titel

Angina pectoris and coronary artery disease in isolated, severe aortic regurgitation

Ist Teil von

• The American journal of cardiology, 1986-03, Vol.57 (8), p.649-651

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

1986

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• Seventy-eight patients with isolated, severe aortic regurgitation (AR) were studied retrospectively to determine the prevalence of angiographically significant coronary artery disease (CAD) and its relation to angina pectoris (AP). Angiographically, significant CAD was present in 29 of 78 patients (37%), and 36 patients (46%) had AP. Twenty-one of 36 patients (58%) with AP and 8 of 42 patients (19%) without AP had angiographically significant CAD. AP as a predictor of significant CAD had a sensitivity of 73%, specificity of 69% and a risk ratio of 3:1. The predictive accuracy of detecting CAD in the absence of AP was 81%. The benefit from concomitant coronary artery bypass grafting at the time of aortic valve replacement for AR has not been clearly demonstrated; therefore, routine coronary angiography is still recommended for all AR patients older than 40 years undergoing aortic valve replacement.