Biochemical and biophysical research communications, 1994-06, Vol.201 (2), p.748-755
1994
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Details
- Autor(en) / Beteiligte
- Titel
- The Nitric Oxide-Scavenging Properties of Ginkgo Biloba Extract EGb 761
- Ist Teil von
- Biochemical and biophysical research communications, 1994-06, Vol.201 (2), p.748-755
- Ort / Verlag
- United States: Elsevier Inc
- Erscheinungsjahr
- 1994
- Quelle
- Elsevier ScienceDirect Journals
- Beschreibungen/Notizen
- Ginkgo biloba extract EGb 761 was found to be a scavenger of nitric oxide in in vitro acellular systems, under physiological conditions. EGb 761 competed with oxyhemoglobin for reaction with nitric oxide generated during the interaction Complex I of catalase. An EGb 761 dose-dependent decrease in the amount of nitrite formed in the reaction of oxygen with nitric oxide produced from solution of 5mM sodium nitroprusside was also observed. These data implicate it as a potential therapeutic agent in conditions of altered production of nitric oxide.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0006-291XeISSN: 1090-2104DOI: 10.1006/bbrc.1994.1764Titel-ID: cdi_proquest_miscellaneous_76541134
- Format
- –
- Schlagworte
- Animals, Catalase - metabolism, Cattle, Free Radical Scavengers, Ginkgo biloba, Glucose Oxidase - metabolism, Kinetics, Nitric Oxide - chemistry, Nitrites - analysis, Nitroprusside - chemistry, Oxyhemoglobins - chemistry, Oxyhemoglobins - metabolism, Plant Extracts - chemistry, Plant Extracts - pharmacology