The Journal of urology, 1994-03, Vol.151 (3), p.561-566
1994
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Details
- Autor(en) / Beteiligte
- Titel
- Hereditary Papillary Renal Cell Carcinoma
- Ist Teil von
- The Journal of urology, 1994-03, Vol.151 (3), p.561-566
- Ort / Verlag
- Hagerstown, MD: Elsevier Inc
- Erscheinungsjahr
- 1994
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- We describe a 3 generation family with members affected with papillary renal cell carcinoma, an uncommon histological type of renal cell carcinoma. Multiple tumors of varying size were present in both kidneys of affected family members. The disorder was not linked to polymorphic markers on chromosome 3p and there was no loss of heterozygosity at loci on 3p in renal tumors. The results suggest the presence of a renal cell carcinoma gene not located on 3p that predisposes to renal cell carcinoma with a distinct histological appearance. The inherited disorder in this family appears to be different from recognized hereditary cancer syndromes.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0022-5347eISSN: 1527-3792DOI: 10.1016/S0022-5347(17)35015-2Titel-ID: cdi_proquest_miscellaneous_76351715
- Format
- –
- Schlagworte
- Adolescent, Adult, Aged, Aged, 80 and over, Biological and medical sciences, carcinoma, renal cell, Carcinoma, Renal Cell - genetics, Female, Genetic Linkage, hereditary diseases, Humans, Karyotyping, kidney neoplasms, Kidney Neoplasms - genetics, Kidneys, Male, Medical sciences, Middle Aged, Nephrology. Urinary tract diseases, Tumors of the urinary system