Details

Autor(en) / Beteiligte

• Fuller, MF
• Milne, A
• Harris, CI
• Reid, TM
• Keenan, R

Titel

Amino acid losses in ileostomy fluid on a protein-free diet

Ist Teil von

• The American journal of clinical nutrition, 1994-01, Vol.59 (1), p.70-73

Ort / Verlag

Bethesda, MD: Elsevier Inc

Erscheinungsjahr

1994

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The contribution of losses via the gastrointestinal tract to maintenance amino acid requirements was assessed by collecting the ileostomy fluid of volunteers given a protein-free diet for 5 d. The subjects were eight adult men and women with terminal ileum ileostomies after ulcerative colitis. Four consecutive 24-h collections of both digesta and urine were made. On the last 2 d an antibiotic was given that suppressed microbial activity in the digesta and slightly reduced ileostomy outflow. Mean daily amino acid excretion in ileostomy fluid ranged from 32 mg/d for methionine to ≈ 330 mg/d for aspartate and glutamate. These losses were compared with current international estimates of amino acid requirements. For most essential amino acids gastrointestinal losses accounted for 14–33% of daily maintenance requirements but for threonine the contribution was 61%.