Details

Autor(en) / Beteiligte

• Mayer-Jaekel, Regina E.
• Hemmings, Brian A.

Titel

Protein phosphatase 2A — a ‘ménage à trois’

Ist Teil von

• Trends in Cell Biology, 1994-08, Vol.4 (8), p.287-291

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

1994

Quelle

Elsevier ScienceDirect Journals

Beschreibungen/Notizen

• Protein phosphorylation is probably the major regulatory mechanism employed by eukaryotic cells. Much work has been devoted to the role of protein kinases and their modulation by hormones, growth factors and neurotransmitters. It is now appreciated that protein phosphatases are also key players in actively regulating many cellular processes. In this article we discuss recent advances in our understanding of the function of protein phosphatase 2A, one of the major serine/threonine-specific protein phosphatases.