Details

Autor(en) / Beteiligte

• NAKATANI, T
• ANAI, H
• TAKANO, H
• TAENAKA, Y
• AKAGI, H
• MASUZAWA, T
• BABA, Y
• SAKAKI, M
• ARAKI, K
• INOUE, K
• MATSUO, Y

Titel

An implantable left ventricular assist system with an electrical impedance monitoring and control system

Ist Teil von

• ASAIO journal (1992), 1993-07, Vol.39 (3), p.M644-M648

Ort / Verlag

Philadelphia, PA: Lippincott

Erscheinungsjahr

1993

Quelle

MEDLINE

Beschreibungen/Notizen

• The authors developed an implantable left ventricular assist system (LVAS) for bridge to transplant of rather small sized adults. The pump was made of segmented polyether polyurethane and was 86 mm in diameter, 50 mm in height, with a 70 ml nominal stroke volume. A percutaneous drive line was connected with an external pneumatic control drive unit (CDU). In chronic animal experiments using 11 adult goats, the pump was installed between the LV apex and the descending aorta and was placed in the abdominal wall. Five goats were killed after 4 to 14 weeks while in good physical condition, and one is ongoing. There were no prominent thromboembolic symptoms despite no anti-thrombogenic agent being used. The new electrical impedance-based monitoring and control system (Z system) was installed in the CDU. In this Z system, automatic calibration was performed periodically for several seconds while the drive condition was changed to ensure full-fill of the blood pump. The full-fill to full-empty drive was well controlled by this Z system. In conclusion, the new Z system is practical and useful for monitoring and control of an implantable pump, giving this LVAS a promising place in clinical use.