Details

Autor(en) / Beteiligte

• GRAUER, L
• PADILLA, V. M
• BOUZA, L
• BARKIN, J. S

Titel

Eosinophilic sclerosing cholangitis associated with hypereosinophilic syndrome

Ist Teil von

• The American journal of gastroenterology, 1993-10, Vol.88 (10), p.1764-1769

Ort / Verlag

Oxford: Blackwell Publishing

Erscheinungsjahr

1993

Quelle

MEDLINE

Beschreibungen/Notizen

• We describe the case of a 41-yr-old man who presented with signs and symptoms of cholestasis including abdominal pain, jaundice, and fever, with peripheral eosinophilia of 10% and bone marrow eosinophilia. Liver biopsy revealed an eosinophilic infiltrate and an ERCP demonstrated bile duct changes, compatible with primary sclerosing cholangitis (PSC). After treatment with prednisone and ursodeoxycholic acid, the patient's liver profile tests returned to normal, the ERCP changes resolved, and all symptoms disappeared. A literature review has not shown any previous reports of reversible sclerosing cholangitis, secondary to eosinophilic infiltration. The purpose of this report is to describe eosinophilic cholangitis, an entity that mimics PSC in the context of the hypereosinophilic syndrome.