The New England journal of medicine, 1993-11, Vol.329 (21), p.1531-1538
1993
Details
- Autor(en) / Beteiligte
- Titel
- Pheochromocytomas, Multiple Endocrine Neoplasia Type 2, and von Hippel-Lindau Disease
- Ist Teil von
- The New England journal of medicine, 1993-11, Vol.329 (21), p.1531-1538
- Ort / Verlag
- Boston, MA: Massachusetts Medical Society
- Erscheinungsjahr
- 1993
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Pheochromocytomas are a feature of two disorders with an autosomal dominant pattern of inheritance -- multiple endocrine neoplasia type 2 (MEN-2) and von Hippel-Lindau disease. Persons carrying the MEN-2 mutation are predisposed to have C-cell hyperplasia or medullary thyroid carcinoma, pheochromocytoma, and hyperparathyroidism (in the MEN-2A subtype) or mucosal neuromas and marfanoid habitus (in the MEN-2B subtype) 1 , 2 . The major components of von Hippel-Lindau disease are retinal angioma, hemangioblastoma of the central nervous system, renal cysts and carcinoma, pheochromocytoma, pancreatic cysts, and epididymal cystadenoma 3 – 8 . Affected members of families with these disorders (carriers) may have one or several . . .
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJM199311183292103Titel-ID: cdi_proquest_miscellaneous_76001886
- Format
- –
- Schlagworte
- Abdomen, Adenomatosis, Familial endocrine, Adolescent, Adrenal Gland Neoplasms - complications, Adrenal Gland Neoplasms - diagnosis, Adrenal Gland Neoplasms - genetics, Adrenals. Adrenal axis. Renin-angiotensin system (diseases), Adult, Aged, Aged, 80 and over, Biological and medical sciences, Catecholamines, Central nervous system, Child, Computed tomography, Cysts, Diagnosis, Endocrinopathies, Female, Genetics, Heredity, Heterozygote, Humans, Hyperparathyroidism, Hypertension, Iodine, Kidney cancer, Localization, Magnetic resonance imaging, Male, Medical imaging, Medical sciences, Men, Middle Aged, Morbidity, Mortality, Multiple endocrine neoplasia, Multiple Endocrine Neoplasia - complications, Multiple Endocrine Neoplasia - diagnosis, Multiple Endocrine Neoplasia - genetics, Neoplasia, Nervous system, Neuroendocrine tumors, Neuroimaging, NMR, Non tumoral diseases. Target tissue resistance. Benign neoplasms, Nuclear magnetic resonance, Pancreas, Pancreatic carcinoma, Parathyroid, Patients, Pedigree, Phakomatoses, Pheochromocytoma, Pheochromocytoma - complications, Pheochromocytoma - diagnosis, Pheochromocytoma - genetics, Plasma, Renal cell carcinoma, Retina, Scintigraphy, Statistical analysis, Thyroid, Thyroid cancer, Tumors, Ultrasonic imaging, Ultrasound, Urine, Von Hippel-Lindau disease, von Hippel-Lindau Disease - complications, von Hippel-Lindau Disease - diagnosis, von Hippel-Lindau Disease - genetics