MICROBIOLOGY and IMMUNOLOGY, 1993, Vol.37(5), pp.411-414
1993
Details
- Autor(en) / Beteiligte
- Titel
- Identification and Characterization of Heat-Stable Enterotoxin II-Producing Escherichia coli from Patients with Diarrhea
- Ist Teil von
- MICROBIOLOGY and IMMUNOLOGY, 1993, Vol.37(5), pp.411-414
- Ort / Verlag
- Tokyo: Blackwell Publishing Ltd
- Erscheinungsjahr
- 1993
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Stock strains of Eschericia coli isolated from patients with traveller's diarrhea were examined for production of heat-stable enterotoxin II (STII). Of 400 strains examined, 3 were found to produce STII. The nucleotide sequence of the STII gene of these human strains was shown to be identical to that of porcine strains. Cultured cells of these strains induced fluid accumulation in ligated mouse intestinal loops and the activity was neutralized by anti-STII antiserum. These results suggest that STII-produciing enterotoxigenic E. coli can cause human diarrhea.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0385-5600eISSN: 1348-0421DOI: 10.1111/j.1348-0421.1993.tb03230.xTitel-ID: cdi_proquest_miscellaneous_75931607
- Format
- –
- Schlagworte
- Animals, Bacterial diseases, Bacterial diseases of the digestive system and abdomen, Bacterial Toxins - genetics, Bacterial Toxins - isolation & purification, Base Sequence, Biological and medical sciences, Diarrhea, Diarrhea - microbiology, DNA, Bacterial - genetics, Enteritis - microbiology, Enterotoxins - genetics, Enterotoxins - isolation & purification, Escherichia coli, Escherichia coli - isolation & purification, Escherichia coli - metabolism, Escherichia coli Infections - microbiology, Escherichia coli Proteins, Feces - microbiology, Genes, Bacterial - genetics, Heat-stable enterotoxin, Human bacterial diseases, Humans, Infectious diseases, Intestine, Small - microbiology, Medical sciences, Mice, Molecular Sequence Data, Polymerase Chain Reaction, Travel