Clinical orthopaedics and related research, 1993-08 (293), p.302-306
1993
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- Autor(en) / Beteiligte
- Titel
- Serial thallium-201 scintigraphy in osteosarcoma : correlation with tumor necrosis after preoperative chemotherapy
- Ist Teil von
- Clinical orthopaedics and related research, 1993-08 (293), p.302-306
- Ort / Verlag
- Heidelberg: Springer
- Erscheinungsjahr
- 1993
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- In 27 patients with extremity lesions (24 osteosarcoma, three malignant fibrous histiocytoma), a notable decrease in thallium-201 uptake was correlated with a good response to preoperative chemotherapy of the primary tumor. A good response is indicated by a greater than 95% tumor necrosis. Serial quantitative thallium-201 uptake of malignant bone tumors in patients receiving preoperative chemotherapy therefore can accurately predict a good histologic response and prognosis. Serial thallium scintigraphy can furthermore identify poor responses within two weeks after the initiation of treatment, or can prompt an early change in preoperative chemotherapy and facilitate limb salvage surgery.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0009-921XeISSN: 1528-1132DOI: 10.1097/00003086-199308000-00040Titel-ID: cdi_proquest_miscellaneous_75856159
- Format
- –
- Schlagworte
- Adolescent, Antineoplastic Combined Chemotherapy Protocols - therapeutic use, Biological and medical sciences, Bone Neoplasms - diagnostic imaging, Bone Neoplasms - drug therapy, Bone Neoplasms - surgery, Chemotherapy, Adjuvant, Diseases of the osteoarticular system, Female, Histiocytoma, Benign Fibrous - diagnostic imaging, Histiocytoma, Benign Fibrous - drug therapy, Histiocytoma, Benign Fibrous - surgery, Humans, Male, Medical sciences, Osteosarcoma - diagnostic imaging, Osteosarcoma - drug therapy, Osteosarcoma - surgery, Radionuclide Imaging, Thallium Radioisotopes, Tumors of striated muscle and skeleton