Clinical neuropharmacology, 1984-01, Vol.7 (4), p.347-350
1984
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Details
- Autor(en) / Beteiligte
- Titel
- Steroid receptors in intracranial tumors
- Ist Teil von
- Clinical neuropharmacology, 1984-01, Vol.7 (4), p.347-350
- Ort / Verlag
- United States
- Erscheinungsjahr
- 1984
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Cytosolic estrogen (ER), progesterone (PR), androgen (AR), and glucocorticoid (GR) receptors were evaluated in 6 meningiomas and 12 gliomas (6 astrocytomas and 6 glioblastomas) using a dextran-coated charcoal method. Thirty-three percent (two) of the meningiomas and 17% (two) of the gliomas contained positive (greater than or equal to 10 fmol/mg protein) but low ER levels. On the other hand, positive PR, GR, and AR levels were detectable in 100% (six) of the meningiomas. PR was present in 50% (six), AR in 42% (five), and GR in 58% (seven) of the gliomas. PR, GR, and AR values were statistically higher in meningiomas than in neuroepithelial tumors.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0362-5664DOI: 10.1097/00002826-198412000-00013Titel-ID: cdi_proquest_miscellaneous_75804798
- Format
- –
- Schlagworte
- Adolescent, Adult, Aged, Brain Neoplasms - metabolism, Child, Child, Preschool, Female, Glioma - metabolism, Humans, Kinetics, Male, Meningeal Neoplasms - metabolism, Meningioma - metabolism, Middle Aged, Receptors, Androgen - metabolism, Receptors, Estrogen - metabolism, Receptors, Glucocorticoid - metabolism, Receptors, Progesterone - metabolism, Receptors, Steroid - metabolism