Details

Autor(en) / Beteiligte

• Tasca, Giordano
• Brunelli, Federico
• Cirillo, Marco
• Amaducci, Andrea
• Mhagna, Zen
• Troise, Giovanni
• Quaini, Eugenio

Titel

Mass regression in aortic stenosis after valve replacement with small size pericardial bioprosthesis

Ist Teil von

• The Annals of thoracic surgery, 2003-10, Vol.76 (4), p.1107-1113

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

2003

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• The aim of the study was to determine whether left ventricular mass regression is influenced by valve size after the implantation of a Carpentier-Edwards Perimount (CEP) pericardial bioprosthesis for pure aortic stenosis. Patients receiving 19-mm, 21-mm, and 23-mm CEP aortic valves underwent echocardiography preoperatively and at least 1 year after surgery (mean, 2.3 ± 1 years) and the echocardiograms were compared within and between groups. The study involved a total of 88 patients: 34 receiving 19-mm CEPs, 29 receiving 21-mm CEPs, and 25 receiving 23-mm CEPs. The mean postoperative prosthetic gradients were respectively 20.6 ± 6.6 mm Hg, 17.9 ± 5.8 mm Hg, and 13.2 ± 4.1 mm Hg ( p = 0.0001); the mean postoperative valve areas were respectively 1.24 ± 0.16 cm 2, 1.45 ± 0.2 cm 2, and 1.63 ± 0.21 cm 2 ( p = 0.0001). In comparison with the preoperative echocardiographic measurements absolute left ventricular mass significantly decreased by −54.1 ± 48.8 g, −54.1 ± 55.1 g, and −74.4 ± 57.4 g respectively with no statistically significant between-group difference (analysis of variance) but ventricular septum and posterior wall thickness significantly decreased in each group ( p < 0.05). The implantation of 19-mm, 21-mm, and 23-mm CEP aortic prostheses significantly reduces left ventricular mass without any size-related differences.