Details

Autor(en) / Beteiligte

• Jenkins, D.J.A
• Kendall, C.W.C
• Faulkner, D.A
• Kemp, T
• Marchie, A
• Nguygen, T.H
• Wong, J.M.W
• de Souza, R
• Emam, A
• Vidgen, E

Titel

Long-term effects of a plant-based dietary portfolio of cholesterol-lowering foods on blood pressure

Ist Teil von

• European journal of clinical nutrition, 2008-06, Vol.62 (6), p.781-788

Ort / Verlag

Basingstoke: Nature Publishing

Erscheinungsjahr

2008

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• Objective: To determine the effect on blood pressure of dietary advice to consume a combination of plant-based cholesterol-lowering foods (dietary portfolio). Methods: For 1 year, 66 hyperlipidemic subjects were prescribed diets high in plant sterols (1.0 g/1000 kcal), soy protein (22.5 g/1000 kcal), viscous fibers (10 g/1000 kcal) and almonds (22.5 g/1000 kcal). There was no control group. Seven-day diet record, blood pressure and body weight were monitored initially monthly and later at 2-monthly intervals throughout the study. Results: Fifty subjects completed the 1-year study. When the last observation was carried forward for non-completers (n=9) or those who changed their blood pressure medications (n=7), a small mean reduction was seen in body weight 0.70.3 kg (P=0.036). The corresponding reductions from baseline in systolic and diastolic blood pressure at 1 year (n=66 subjects) were - 4.21.3 mm Hg (P=0.002) and - 2.30.7 mm Hg (P=0.001), respectively. Blood pressure reductions occurred within the first 2 weeks, with stable blood pressures 6 weeks before and 4 weeks after starting the diet. Diastolic blood pressure reduction was significantly related to weight change (r=0.30, n=50, P=0.036). Only compliance with almond intake advice related to blood pressure reduction (systolic: r=- 0.34, n=50, P=0.017; diastolic: r=- 0.29, n=50, P=0.041). Conclusions: A dietary portfolio of plant-based cholesterol-lowering foods reduced blood pressure significantly, related to almond intake. The dietary portfolio approach of combining a range of cholesterol-lowering plant foods may benefit cardiovascular disease risk both by reducing serum lipids and also blood pressure.