Details

Autor(en) / Beteiligte

• Smith, David W.E.
• Randazzo, Randall F.
• McNamara, Anne L.

Titel

The tRNA content of non-hemoglobinized red cell precursors: Evidence that tRNA content is controlled by tRNA utilization

Ist Teil von

• Biochemical and biophysical research communications, 1980-07, Vol.95 (1), p.468-473

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

1980

Link zum Volltext

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• The content of tRNA's accepting several amino acids was determined for the non-hemoglobinized early precursors of rabbit red cells and was compared with the tRNA content of rabbit reticulocytes and liver. The specialization of the tRNA content for hemoglobin synthesis seen in reticulocytes was not seen in the earlier precursors, suggesting that tRNA specialization does not occur before the onset of hemoglobin synthesis. The results favor hypotheses that the tRNA content develops in response to tRNA utilization in translation.