Details

Autor(en) / Beteiligte

• Cornhill, J.Fredrick
• Levesque, Murina J.
• Herderick, Edward E.
• Nerem, Robert M.
• Kilman, James W.
• Vasko, John S.

Titel

Quantitative study of the rabbit aortic endothelium using vascular casts

Ist Teil von

• Atherosclerosis, 1980-03, Vol.35 (3), p.321-337

Ort / Verlag

Ireland: Elsevier Ireland Ltd

Erscheinungsjahr

1980

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• A quantitative study of the en face size and shape of rabbit endothelial cells from the ventral mid-thoracic and ventral infrarenal abdominal aorta has been carried out in 6 rabbits. Photomicrographs were taken from vascular casts of the rabbit aorta and the endothelial cell outlines were analyzed quantitatively using a digitizer and digital computer. The morphology of the endothelial cells was described using 8 calculated parameters (area, perimeter, length, width, angle of orientation, width:length ratio, axis intersection ratio and shape index). The endothelial cells in both locations had the same surface area ( P > 0.30); however, the cells in the abdominal aorta were longer ( P < 0.01) and narrower ( P < 0.01) than those in the thoracic aorta. This fact is reflected by the smaller value for the shape index and width : length ratio in the abdominal aorta ( P < 0.01). Cells in both the thoracic and abdominal aorta were aligned with the flow direction.