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British journal of haematology, 1971-08, Vol.21 (2), p.153-164
1971
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Details

Autor(en) / Beteiligte
Titel
The Sequestration Site of Platelets in Idiopathic Thrombocytopenic Purpura: its Correlation with the Results of Splenectomy
Ist Teil von
  • British journal of haematology, 1971-08, Vol.21 (2), p.153-164
Ort / Verlag
Oxford, UK: Blackwell Publishing Ltd
Erscheinungsjahr
1971
Quelle
MEDLINE
Beschreibungen/Notizen
  • The clinical usefulness of external scanning data after infusion of 51Crlabelled platelets into patients with idiopathic thrombocytopenic purpura (ITP) is a matter of controversy. Observations have been made in 575 patients with ITP. Short‐term (6 mth) results of splenectomy were assessed in 206 subjects, and longterm (1‐3 yr) in 153. It appears that the site of sequestration is neither a direct function of the severity of the disease nor of the duration of the disease from the clinical onset. Diffuse sequestration, which cannot be taken as an indication for or against splenectomy, is frequently seen in recent and severe cases. Splenic sequestration is more often observed in young patients (72.5% under 30 yr of age) than in older subjects (36% over 30 yr of age). A good correlation was found between the site of sequestration and the shortand long‐term results of splenectomy: success in more than 90% of cases with splenic sequestration but complete failure in 70% with hepatic sequestration. In any patient with ITP splenectomy should be undertaken only after a careful study of the platelet sequestration site.
Sprache
Englisch
Identifikatoren
ISSN: 0007-1048
eISSN: 1365-2141
DOI: 10.1111/j.1365-2141.1971.tb03425.x
Titel-ID: cdi_proquest_miscellaneous_74903979

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