Details

Autor(en) / Beteiligte

• Guinjoan, Salvador M
• Mayberg, Helen S
• Costanzo, Elsa Y
• Fahrer, Rodolfo D
• Tenca, Eduardo
• Antico, Julio
• Cerquetti, Daniel
• Smyth, Elisa
• Leiguarda, Ramón C
• Nemeroff, Charles B

Titel

Asymmetrical contribution of brain structures to treatment-resistant depression as illustrated by effects of right subgenual cingulum stimulation

Ist Teil von

• The journal of neuropsychiatry and clinical neurosciences, 2010-01, Vol.22 (3), p.265-277

Erscheinungsjahr

2010

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Major depressive disorder is one of the most common psychiatric disorders, with a worldwide lifetime prevalence rate of 10%-20% in women and a slightly lower rate in men. While many patients are successfully treated using established therapeutic strategies, a significant percentage of patients fail to respond. This report describes the successful recovery of a previously treatment-resistant patient following right unilateral deep brain stimulation of Brodmann's area 25. Current therapeutic approaches to treatment-resistant patients are reviewed in the context of this case with an emphasis on the role of the right and left hemispheres in mediating disease pathogenesis and clinical recovery.