Science China. Life sciences, 2009-12, Vol.52 (12), p.1117-1122
2009
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Details
- Autor(en) / Beteiligte
- Titel
- Circulating miRNA and cancer diagnosis
- Ist Teil von
- Science China. Life sciences, 2009-12, Vol.52 (12), p.1117-1122
- Ort / Verlag
- Beijing: Science China Press
- Erscheinungsjahr
- 2009
- Quelle
- SpringerLink
- Beschreibungen/Notizen
- miRNAs are a class of small RNA molecules with regulatory function, and play an important role in tumor development and progression. It has been demonstrated that tumor-derived miRNAs exist in the circulating nucleic acids of cancer patients. This phenomenon implies that detection of the circulating miRNA may be an effective method for non-invasive diagnosis of cancer. In this review, we summarize the applications of the circulating miRNA as biomarkers in cancer diagnosis, as well as the latest research progress in this area.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1674-7305, 1006-9305eISSN: 1869-1889, 1862-2798DOI: 10.1007/s11427-009-0158-5Titel-ID: cdi_proquest_miscellaneous_746154248
- Format
- –
- Schlagworte
- Animals, Biomarkers, Tumor - blood, Biomarkers, Tumor - genetics, Biomedical and Life Sciences, cancer, circulating, diagnosis, Humans, Life Sciences, MicroRNAs - blood, MicroRNAs - genetics, miRNA, Neoplasms - blood, Neoplasms - diagnosis, Neoplasms - genetics, Reverse Transcriptase Polymerase Chain Reaction, Review, Sensitivity and Specificity