Details

Autor(en) / Beteiligte

• El Asslouj, Jaouad (Laboratory of Environmental Metrology, University Hassan I, FST Settat, Morocco)
• Amahdar, Loubna (Research Group on Toxicogenetics and Mutagenesis, Laboratory of Agrofood and Health, University Hassan I, FST Settat, Morocco)
• Glouib, Kamal (Research Group on Toxicogenetics and Mutagenesis, Laboratory of Agrofood and Health, University Hassan I, FST Settat, Morocco)
• Kholtei, Sanae (Laboratory of Environmental Metrology, University Hassan I, FST Settat, Morocco)
• El Amrani Paaza, Namira (Laboratory of Applied Geology, University Hassan I, FST Settat, Morocco)
• Verschaeve, Luc (Department of Epidemiology and Toxicology, Scientific Institute of Public Health, Brussels, Belgium)
• Hilali, Abderraouf (Research Group on Toxicogenetics and Mutagenesis, Laboratory of Agrofood and Health, University Hassan I, FST Settat, Morocco)

Titel

In Vitro Genotoxicity of Wastewaters from the Town of Settat, Morocco

Ist Teil von

• Arhiv za higijenu rada i toksikologiju, 2009-09, Vol.60 (3), p.289-296

Ort / Verlag

Croatia: Versita

Erscheinungsjahr

2009

Link zum Volltext

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• In recent years, the town of Settat has seen a considerable industrial growth, which has resulted in increased environmental pollution. This includes pollution by household and industrial wastewaters, which are released into the Boumoussa River without any preliminary treatment. The river valley crosses the community of Mzamza 8 km to the north of the town. Years of drought forced members of the community to use this polluted ground water for irrigation and put themselves and the environment at risk.The aim of this study was to determine the physicochemical and metal profile of Settat wastewaters and to assess their impact on the water table. The second objective was to investigate the genotoxic potential of wastewater on human peripheral blood lymphocytes in vitro, using the micronucleus test and cellular proliferation index.This study demonstrated significant pollution of Boumoussa valley groundwater and of the local wells. Sampled water induced a clear increase in the frequency of micronucleated cells and a lower cell proliferation in human peripheral blood lymphocytes in vitro. Nagli industrijski razvoj u gradu Settatu posljednjih je godina rezultirao povećanim one _išćenjem okoliša, osobito putem otpadnih voda iz kućanstava i industrije. Te se otpadne vode bez ikakve prethodne obrade odlažu u dolinu rijeke Boumoussa na podru _ju zajednice Mzamza, 8 km sjeverno od grada. Uzastopne sušne sezone lokalnoj su zajednici nametnule potrebu za uporabom tih voda za navodnjavanje, _ime su i zajednica i okoliš postali izloženi povećanim rizicima od one _išćenja tla i izvora podzemnih voda. Svrha ovog istraživanja bila je provesti fizikalno-kemijsku karakterizaciju i utvrđivanje sadržaja metala u otpadnim vodama grada Settata te procijeniti njihove u _inke na gornji sloj podzemnih voda. Ujedno je istraživan genotoksi _ni potencijal otpadnih voda u uvjetima in vitro na limfocitima periferne krvi _ovjeka primjenom mikronukleusnog testa i proliferacijskog indeksa. Istraživanje je potvrdilo visok stupanj one _išćenja vodâ u dolini Boumoussa, kao i vodâ iz bunara smještenih u neposrednoj blizini. Štetni su u _inci one _išćenja potvrđeni i na osnovi povišene u _estalosti stanica s mikronukleusima te snižene vrijednosti proliferacijskog indeksa u limfocitima periferne krvi u uvjetima in vitro.