Details

Autor(en) / Beteiligte

• Belokon, Yuri N.
• Chusov, Denis
• Peregudov, Alexander S.
• Yashkina, Lidia V.
• Timofeeva, Galina I.
• Maleev, Victor I.
• North, Michael
• Kagan, Henri B.

Titel

Asymmetric meso-Epoxide Ring-Opening with Trimethylsilyl Cyanide Promoted by Chiral Binuclear Complexes of Titanium. Dichotomy of CC versus CN Bond Formation

Ist Teil von

• Advanced synthesis & catalysis, 2009-12, Vol.351 (18), p.3157-3167

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2009

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• In the presence of chiral catalysts derived from the same chiral hexadentate ligand and aluminium, zinc or titanium ions, the reaction between cyclohexene oxide and trimethylsilyl cyanide can be controlled to give predominantly either the nitrile (up to 99% ee) or the isonitrile product (up to 94% ee). The metal ion, ligand stereochemistry and base concentration all play a role in determining the product ratio.