Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
Zur Ergebnisliste
Ergebnis 1 von 73
    Datensatz exportieren als...
  • BibTeX
KCNQ2 and KCNQ3 Potassium Channel Subunits: Molecular Correlates of the M- Channel
Science (American Association for the Advancement of Science), 1998-12, Vol.282 (5395), p.1890-1893
1998

Details

Autor(en) / Beteiligte
Titel
KCNQ2 and KCNQ3 Potassium Channel Subunits: Molecular Correlates of the M- Channel
Ist Teil von
  • Science (American Association for the Advancement of Science), 1998-12, Vol.282 (5395), p.1890-1893
Ort / Verlag
Washington, DC: American Society for the Advancement of Science
Erscheinungsjahr
1998
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
  • The M-current regulates the subthreshold electrical excitability of many neurons, determining their firing properties and responsiveness to synaptic input. To date, however, the genes that encode subunits of this important channel have not been identified. The blophysical properties, sensitivity to pharmacological blockade, and expression pattern of the KCNQ2 and KCNQ3 potassium channels were determined. It is concluded that both these subunits contribute to the native M-current.
Sprache
Englisch
Identifikatoren
ISSN: 0036-8075
eISSN: 1095-9203
DOI: 10.1126/science.282.5395.1890
Titel-ID: cdi_proquest_miscellaneous_743682441
Format
–
Schlagworte
Adult, Anatomy, Animals, Anthracenes - pharmacology, Biological and medical sciences, Brain - metabolism, Cell membranes. Ionic channels. Membrane pores, Cell structures and functions, Central nervous system, Complementary DNA, Electric potential, Electrophysiology, Fundamental and applied biological sciences. Psychology, Ganglia, Ganglia, Sympathetic - metabolism, Gene Expression, Genes, Humans, Indoles - pharmacology, KCNQ2 Potassium Channel, KCNQ3 Potassium Channel, Kinetics, Messenger RNA, Molecular and cellular biology, Molecular biology, Narcotics, Neurons, Neurons - drug effects, Neurons - physiology, Oocytes, Patch-Clamp Techniques, Physiological aspects, Potassium, Potassium - metabolism, Potassium channels, Potassium Channels - chemistry, Potassium Channels - drug effects, Potassium Channels - genetics, Potassium Channels - metabolism, Potassium Channels, Voltage-Gated, Pyridines - pharmacology, Rats, Sympathetic ganglia, Sympathetic Nervous System - drug effects, Sympathetic Nervous System - physiology, Tetraethylammonium - pharmacology, Xenopus

Weiterführende Literatur

Empfehlungen zum selben Thema automatisch vorgeschlagen von bX