Details

Autor(en) / Beteiligte

• Arbeitman, Michelle N.
• Eileen E. M. Furlong
• Imam, Farhad
• Johnson, Eric
• Null, Brian H.
• Baker, Bruce S.
• Krasnow, Mark A.
• Scott, Matthew P.
• Davis, Ronald W.
• White, Kevin P.

Titel

Gene Expression during the Life Cycle of Drosophila melanogaster

Ist Teil von

• Science (American Association for the Advancement of Science), 2002-09, Vol.297 (5590), p.2270-2275

Ort / Verlag

Washington, DC: American Association for the Advancement of Science

Erscheinungsjahr

2002

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Molecular genetic studies of Drosophila melanogaster have led to profound advances in understanding the regulation of development. Here we report gene expression patterns for nearly one-third of all Drosophila genes during a complete time course of development. Mutations that eliminate eye or germline tissue were used to further analyze tissue-specific gene expression programs. These studies define major characteristics of the transcriptional programs that underlie the life cycle, compare development in males and females, and show that large-scale gene expression data collected from whole animals can be used to identify genes expressed in particular tissues and organs or genes involved in specific biological and biochemical processes.