Details

Autor(en) / Beteiligte

• Wiedemann, E
• Saito, T
• Linfoot, J A
• Li, C H

Titel

Radioimmunoassay of human beta-lipotropin in unextracted plasma

Ist Teil von

• The journal of clinical endocrinology and metabolism, 1977-11, Vol.45 (5), p.1108-1111

Ort / Verlag

United States

Erscheinungsjahr

1977

Quelle

MEDLINE

Beschreibungen/Notizen

• A sensitive and specific radioimmunoassay for human beta-lipotropin (betah-LPH) in unextracted plasma was developed using pur betah-LPH as tracer and standard and an antiserum not cross-reacting with human beta-MSH and hACTH. In healthy volunteers plasma betah-LPH ranged from less than 20 to 150 pg/ml at 8:00 a.m. and rose after metyrapone administration. betah-LPH was very low in panhypopituitarism, normal in most patients with untreated Cushing's disease, elevated in acromegaly and extremely high in Nelson's syndrome.