European journal of pharmacology, 1981-06, Vol.72 (1), p.87-91
1981
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Details
- Autor(en) / Beteiligte
- Titel
- Norepinephrine produces tension through electromechanical coupling in rabbit ear artery
- Ist Teil von
- European journal of pharmacology, 1981-06, Vol.72 (1), p.87-91
- Ort / Verlag
- Netherlands: Elsevier B.V
- Erscheinungsjahr
- 1981
- Quelle
- Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
- Beschreibungen/Notizen
- Membrane potential (E m) and contractile responses to norepinephrine (NE) were measured to determine whether electromechanical coupling is important in the rabbit ear artery. NE contraction and depolarization of the vascular muscle cells were both dose dependent, with a positive correlation between depolarization and tension generated by the vessel. These studies suggest that NE regulates vascular muscle contraction through an E m signal in the rabbit ear artery.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0014-2999eISSN: 1879-0712DOI: 10.1016/0014-2999(81)90301-0Titel-ID: cdi_proquest_miscellaneous_73672296
- Format
- –
- Schlagworte
- Animals, Arteries - drug effects, Arteries - physiology, Biomechanical Phenomena, contraction, Depolarization, Ear - blood supply, Electrophysiology, Female, In Vitro Techniques, Male, Membrane potential, Membrane Potentials - drug effects, Muscle Contraction - drug effects, Muscle, Smooth, Vascular - drug effects, Nonelectrical coupling, Norepinephrine - pharmacology, Rabbits, Vascular muscle, Vasoconstriction, Vasoconstriction - drug effects