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In a pig model ePTFE grafts will sustain for 6 weeks a confluent endothelial cell layer formed in vitro under shear stress conditions
Ist Teil von
European journal of vascular and endovascular surgery, 2003-08, Vol.26 (2), p.156-160
Ort / Verlag
England: Elsevier Ltd
Erscheinungsjahr
2003
Quelle
Free E-Journal (出版社公開部分のみ)
Beschreibungen/Notizen
Objective: to investigate in a pig model whether small diameter ePTFE grafts will sustain a confluent endothelial cell layer formed in vitro under shear stress conditions. Material and Methods: thirteen ePTFE (4 mm) grafts were implanted end to end in the right femoral artery of; 8 grafts had been endothelialized in vitro. Grafts were left in situ for 6 weeks then evaluated with ultrasound and histology. Results: seven endothelialized graft were patent with confluent endothelial cell lining. None of the control grafts were patent or showed evidence of an endothelial lining. Conclusion: in this pig model ePTFE grafts sustained for 6 weeks a confluent endothelial cell layer formed in vitro under shear stress.
Eur J Vasc Endovasc Surg 26, 156-160 (2003)