Details

Autor(en) / Beteiligte

• Barker, Paul D

Titel

Designing redox metalloproteins from bottom-up and top-down perspectives

Ist Teil von

• Current opinion in structural biology, 2003-08, Vol.13 (4), p.490-499

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2003

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• The design of redox-active metalloproteins has been approached from two different directions. The de novo design approach has recently reached an important stage, at which structural information on several different designed metalloproteins has been obtained. This new information highlights the real challenge of this approach. The alternative approach involving re-engineering of evolved proteins has also made significant advances recently.