Details

Autor(en) / Beteiligte

• Carson, Cheryl A
• Kerr, Michael A

Titel

Heterocycles from cyclopropanes: applications in natural product synthesis

Ist Teil von

• Chemical Society reviews, 2009-01, Vol.38 (11), p.3051-3060

Ort / Verlag

England

Erscheinungsjahr

2009

Quelle

MEDLINE

Beschreibungen/Notizen

• The construction of heterocyclic compounds from activated cyclopropane derivatives offers an alternative strategy for the preparation of molecules that may be of interest from a structural or biological standpoint. Several newly developed methods provide access to densely functionalized heterocycles in a manner that can be considered useful for both diversity- and target-oriented synthetic approaches. This tutorial review focuses on the latter, describing recent developments and applications of cyclopropane ring-expansion reactions in natural product synthesis.