Details

Autor(en) / Beteiligte

• Zhang, Ruixing
• Tang, Dan
• Lu, Ping
• Yang, Xiangyu
• Liao, Dongli
• Zhang, Yujing
• Zhang, Mingjun
• Yu, Cong
• Yam, Vivian W. W

Titel

Nucleic Acid-Induced Aggregation and Pyrene Excimer Formation

Ist Teil von

• Organic letters, 2009-10, Vol.11 (19), p.4302-4305

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2009

Quelle

MEDLINE

Beschreibungen/Notizen

• Nucleic acid was found to induce the aggregation of the positively charged pyrene probe (compound 1); as a result, strong pyrene excimer emission was observed. The intensity of the excimer emission was dependent on the concentration of the pyrene probe and the oligonucleotide length, sequence, and concentration. These results suggest a new strategy for label-free nucleic acid-based biosensing applications.