Immunology letters, 2009-09, Vol.126 (1), p.83-84
2009
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Details
- Autor(en) / Beteiligte
- Titel
- In vivo detection of lamellocytes in Drosophila melanogaster
- Ist Teil von
- Immunology letters, 2009-09, Vol.126 (1), p.83-84
- Ort / Verlag
- Netherlands: Elsevier B.V
- Erscheinungsjahr
- 2009
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Abstract Drosophila has recently become a powerful model organism for studies of innate immunity. The cellular elements of innate immunity in Drosophila , the hemocytes, have been characterized by morphological criteria, molecular markers, and cell-type-specific immunological markers. Here we suggest that an MiET1 GFP-reporter element insertion in the untranslated region of a gene ( l1 - atilla ) – expressed in a subset of hemocytes, the lamellocytes – allows in vivo investigations of lamellocyte differentiation and facilitates genetic screens.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0165-2478eISSN: 1879-0542DOI: 10.1016/j.imlet.2009.08.004Titel-ID: cdi_proquest_miscellaneous_734054789
- Format
- –
- Schlagworte
- Allergy and Immunology, Animals, Cell Differentiation, Differentiation, DNA Transposable Elements - genetics, Drosophila, Drosophila melanogaster, Drosophila melanogaster - genetics, Drosophila melanogaster - metabolism, Drosophila Proteins - genetics, Fluorescent Antibody Technique, Indirect, Genetic screening, Green Fluorescent Proteins - genetics, Green Fluorescent Proteins - metabolism, Hemocyte, Hemocyte marker, Hemocytes, Hemocytes - cytology, Hemocytes - metabolism, Immunity, In vivo, Insertion, Lamellocyte, Larva - genetics, Larva - metabolism, Mutagenesis, Insertional