Details

Autor(en) / Beteiligte

• Lukyanova, L. D
• Germanova, E. L
• Kopaladze, R. A

Titel

Development of Resistance of an Organism under Various Conditions of Hypoxic Preconditioning: Role of the Hypoxic Period and Reoxygenation

Ist Teil von

• Bulletin of experimental biology and medicine, 2009-04, Vol.147 (4), p.400-404

Ort / Verlag

Boston: Boston : Springer US

Erscheinungsjahr

2009

Quelle

MEDLINE

Beschreibungen/Notizen

• Single exposure to moderate (10% O₂) hypobaric, normobaric, and intermittent hypoxia is followed by a preconditioning response of the organism. The mechanisms for immediate adaptation are activated during the hypoxic period. Intermittent reoxygenation not only delays, but even suppresses this process. However, periods of oxygenation during the course of hypoxic training reduce the effect of hypoxia and prevent the possibility for “overdosage” of the adverse stimulus. Hence, they have a regulatory or normalizing role under these conditions. Our results indicate that hypoxitherapy in intermittent hypoxia mode provides optimum conditions for long-term adaptation.