Details

Autor(en) / Beteiligte

• Karadeolian, Avedis
• Kerr, Michael A

Titel

Total Synthesis of (+)-Isatisine A

Ist Teil von

• Angewandte Chemie (International ed.), 2010-02, Vol.49 (6), p.1133-1135

Ort / Verlag

Weinheim: Wiley-VCH Verlag

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• Isatis indigotica has long been used as a source of therapeutic compounds in traditional Chinese medicine (the roots are the source of Ben Lan Gen herbal tea). In 2007 the leaves of I. indigotica yielded isatisine A, an unusual oxidized bis‐indole. A concise, enantiospecific total synthesis of isatisine A is reported using a homochiral cyclopropane diester to construct the key tetrahydrofuran ring.