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A study of coagulase-negative staphylococci with reference to slime production, adherence, antibiotic resistance patterns and clinical significance
Ist Teil von
The Journal of hospital infection, 1992-11, Vol.22 (3), p.217-227
Ort / Verlag
Kent: Elsevier Ltd
Erscheinungsjahr
1992
Link zum Volltext
Quelle
Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
Beschreibungen/Notizen
Two hundred and fifty-one strains of coagulase-negative staphylococci (CNS) isolated from patients in hospital and the community were investigated for slime production and adherence as indicators of pathogenicity.
Staphylococcus epidermidis formed 68·5% (126) of the isolates of CNS from blood and central venous catheter (CVC) tips, of which 46·0% (58) were slime-positive and adherent. Clinically significant infections were associated with 55·2% (32) of the slime-positive adherent strains isolated and 11·1% (four) of slime-negative non-adherent strains of
S. epidermidis. For other species of CNS isolated from blood and CVC tips 74·1% (43) were slime negative non-adherent and 18·6% (eight) of these were considered clinically significant isolates while none of the slime positive adherent strains were associated with a clinically significant infection. Slime production and adherence were not characteristic properties of CNS causing community-acquired urinary tract infection or colonizing the nasal mucosa. It is concluded that slime production and adherence had a limited role in the differentiation between clinically significant and contaminant strains isolated from blood cultures; however, the absence of slime and adherence in isolates of
S. epidermidis suggested a lack of pathogenicity.