Details

Autor(en) / Beteiligte

• Sánchez, Hugo
• Albala, Cecilia
• Herlramp F, Eva
• Verdugo, Renato
• Lavados, Manuel
• Castillo, José Luis
• Lera, Lydia
• Uauy, Ricardo

Titel

Prevalence of vitamin B-12 deficiency in older adults

Ist Teil von

• Revista medíca de Chile, 2010-01, Vol.138 (1), p.44-52

Ort / Verlag

Chile

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• There is a correlation between aging and the decrease of plasma levels of vitamin B-12. To determine the prevalence of vitamin B-12 and folate deficiency and its hematological impact among older adults (AM). Cross-sectional study, in 1028 subjects aged 65 to 87years, living in community and evaluated between 2005 and 2008. Percentile distribution of vitamin B-12, folate, hemoglobin, packed red cell volume and mean cell volume by gender and age were analyzed. Deficiency was defined as vitamin B-12 levels < 148 pmol/L, marginal deficiency as vitamin B-12 levels < 221 pmol/L, anemia was defined as a hemoglobin < 13 and 12 g/dL among men and women, respectively. The prevalence of vitamin B-12 deficiency was 12% and the figure for marginal deficiency was 25.4%. Males were more affected than females (p < 0.001). The frequency of anemia was 8.6%o, and was higher among women (p = 0.004). There is a high prevalence of full blown and marginal deficit of vitamin B-12 among the elderly. This deficiency should be considered for correction through public nutrition policies.